Publications (click titles to link to open access articles- more coming soon)

Suminaite D, Lyons DA, Livesey M.
Myelinated axon physiology and regulation of neural circuit function.
Glia (2019) doi: 10.1002/glia.23665

Yang Z, Cole KLH, Qiu Y, Somorjai IML, Wijesinghe P, Nylk J, Cochran S, Spalding GC, Lyons DA, Dholakia K.
Light sheet microscopy with acoustic sample confinement.
Nat Commun. (2019) 10(1):669. doi: 10.1038/s41467-019-08514-5.

Allen NJ, Lyons DA
Glia as architects of central nervous system formation and function
Science (2018) 362(6411):181-185

Early JJ, Cole KL, Williamson JM, Swire M, Kamadurai H, Muskavitch M, Lyons DA.
An automated high-resolution in vivo screen in zebrafish to identify chemical regulators of myelination.
 eLife (2018) pii: e35136. doi: 10.7554/eLife.35136

Almeida RG, Pan S, Cole KLH, Williamson JM, Early JJ, Czopka T, Klingseisen A, Chan JR, Lyons DA.
Myelination of Neuronal Cell bodies when myelin sheaths exceeds axonal demand.
Current Biology
(2018) doi: 10.1016/j.cub.2018.02.068.

Baraban M, Koudelka S and Lyons DA.
Ca2+ activity signatures of myelin sheath formation and growth in vivo.
Nature Neuroscience (2018) 21(1):19-23

Almeida RG, Lyons DA.
On Myelinated Axon Plasticity and Neuronal Circuit Formation and Function.
Journal of Neuroscience (2017) 37(42):10023-10034.

Cole KLH, Early JJ, Lyons DA.
Drug discovery for remyelination and treatment of MS.
Glia (2017) 65(10):1565-1589.

Klingseisen A, Lyons DA.
Axonal Regulation of Central Nervous System Myelination: Structure and Function
The Neuroscientist (2017) doi: 10.1177/1073858417703030. 

Karttunen MJ, Czopka T, Goedhart M, Early JJ, Lyons DA.
Regeneration of myelin sheaths of normal length and thickness in the zebrafish CNS correlates with growth of axons in caliber.
PLoS One (2017) 12(5):e0178058.

Redmond SA, Mei F, Eshed-Eisenbach Y, Osso LA, Leshkowitz D, Shen YA, Kay JN, Aurrand-Lions M, Lyons DA, Peles E, Chan JR. 
Somatodendritic Expression of JAM2 Inhibits Oligodendrocyte Myelination.
Neuron (2016) 91(4):824-36

Bin JM and Lyons DA.
Imaging Myelination In Vivo Using Transparent Animal Models
Brain Plasticity (2016)  2(1): 3-29

Almeida RG and Lyons D.
Oligodendrocyte Development in the Absence of Their Target Axons In Vivo.
PLoS ONE (2016) 11(10):e0164432.

Koudelka S, Voas MG, Almeida RG, Baraban M, Soetaert J, Meyer MP, Talbot WS and Lyons DA.
Individual Neuronal Subtypes Exhibit Diversity in CNS Myelination Mediated by Synaptic Vesicle Release.
Current Biology (2016) 26(11):1447-55

Almeida RG and Lyons DA.
Intersectional Gene Expression in Zebrafish Using the Split KalTA4 System.
Zebrafish (2015) doi:10.1089/zeb.2015.1086

Nawaz S, Sánchez P, Schmitt S, Snaidero N, Mitkovski M, Velte C, Brückner BR, Alexopoulos I, Czopka T, Jung SY, Rhee JS, Janshoff A, Witke W, Schaap IA, Lyons DA, Simons M.
Actin Filament Turnover Drives Leading Edge Growth during Myelin Sheath Formation in the Central Nervous System.
Developmental Cell (2015) 34(2):139-51

Mensch S, Baraban M, Almeida R, Czopka T, Ausborn J, El Manira A, Lyons DA.
Synaptic vesicle release regulates myelin sheath number of individual oligodendrocytes in vivo.
Nature Neuroscience (2015) 18(5):628-30      

Baraban M, Mensch S, Lyons DA.
Adaptive myelination from fish to man.
Brain Research (2016) 1641(Pt A):149-61.

Snaidero N, Möbius W, Czopka T, Hekking LH, Mathisen C, Verkleij D, Goebbels S, Edgar J, Merkler D, Lyons DA, Nave KA, Simons M.
Myelin Membrane Wrapping of CNS Axons by PI(3,4,5)P3-Dependent Polarized Growth at the Inner Tongue.
Cell. (2014) 156(1-2):277-90.

Almeida RG and Lyons DA
On the resemblance of synapse formation and CNS myelination.
Neuroscience (2014) 276:98-108

Lyons DA and Simons M
Axonal selection and myelin membrane biogenesis in the central nervous system
Current Opinions in Cell Biology (2013) 25(4):512-9

Czopka, T, ffrench-Constant C, and Lyons DA.
Individual oligodendrocytes have only a few hours in which to generate new myelin sheaths in vivo.
Developmental Cell (2013) 25(6):599-609.

Almeida RG, Czopka, T, ffrench-Constant C, and Lyons DA.
Individual axons regulate the myelinating potential of single oligodendrocytes in vivo.
Development (2011) 138: 4443-4450

Raphael AR, Lyons DA and Talbot WS.
ErbB signaling has a role in radial sorting independent of Schwann cell number.
Glia (2011) 59: 1047-55

Lyons DA, Naylor SG, Scholze, and Talbot WS.
Kif1b is essential for mRNA localization in oligodendrocytes and development of myelinated axons.
Nature Genetics. (2009) 41: 854-858.

Lyons DA, Naylor SG, Mercurio S, Dominguez C, and Talbot WS.
KBP is essential for axonal structure, outgrowth, and maintenance in zebrafish, providing insight into the cellular basis of Goldberg-Shprintzen syndrome.
Development. (2008) 135: 599-608

Tawk M, Araya C, Lyons DA, Reugels AM, Girdler GC, Bayley PR, Hyde DR, Tada M and Clarke JD.
A mirror-symmetric cell division that orchestrates neuroepithelial morphogenesis.
Nature (2007) 446: 797-800

Voas MG, Lyons DA, Naylor SG, Arana N, Rasband MN and Talbot WS. alphaII-Spectrin Is Essential for Assembly of the Nodes of Ranvier in Myelinated Axons.
Current Biology (2007) 17: 562-8.

Pogoda HM, Sternheim N, Lyons DA, Diamond B, Hawkins TA, Woods IG, Bhatt DH, Franzini-Armstrong C, Dominguez C, Arana N, Jacobs J, Nix R, Fetcho JR,and Talbot WS.
A genetic screen identifies genes essential for development of myelinated axons in zebrafish.
Developmental Biology (2006) 298(1):118-31.

Woods IG, Lyons DA, Voas MG, Pogoda HM and Talbot WS.
nsf is essential for organization of myelinated axons in zebrafish.
Current Biology (2006) 16: 636-48.

Lyons DA, Pogoda HM, Voas MG, Woods IG, Diamond B, Nix R, Arana N, Jacobs J, and Talbot WS.
erbb3 and erbb2 are essential for Schwann cell migration and myelination in zebrafish.
Current Biology (2005) 15: 513-524.

Lyons DA, Guy AT and Clarke JDW.
Monitoring neural progenitor fate through multiple rounds of division in an intact vertebrate brain.
Development (2003) 130: 3427-3436.


Lyons DA and Talbot WS
Targeting mechanisms in myelinated axons: not all nodes are created equal.
Developmental Cell (2012) 22:7-9.

Lyons DA and Talbot WS.
Axonal domains: role for paranodal junction in node of Ranvier assembly.
Current Biology (2008) 18:R876-9.

Book Chapters

Lyons DA and Talbot WS.
Glial Cell development and function in zebrafish.
Cold Spring Harb Perspect Biol. (2014) 7(2):a020586.

Czopka T and Lyons DA.
Dissecting mechanisms of myelinated axon formation using zebrafish.
Methods Cell Biology (2011) 105: 25-62